Current Studies
CONRAD Clinical Studies: Active
|
Title and Protocol # |
Summary |
Site(s) |
Status |
|
CONRAD 113 Pharmacokinetics (PK)/Pharmacodynamics (PD) Study of Tenofovir (TFV) Gel |
Assessing local (vaginal) and systemic (blood) levels of TFV with different gel dosing regimens: before and after sex, before sex, after sex, and daily |
Eastern Virginia Medical School (EVMS) PROFAMILIA University of Pittsburgh Advances in Health University of Pennsylvania |
Will be completed in May 90 women |
CONRAD Clinical Studies: Pending
|
Title and Protocol # |
Summary |
Site(s) |
Status |
|
CONRAD 114 Effects of Contraception and Menstrual Cycle on PK/PD and Vaginal Safety in TFV Gel Users |
Effects of Depo-Provera, oral contraceptives and the menstrual cycle on PK/PD and safety of TFV gel |
EVMS PROFAMILIA University of Pittsburgh |
Ongoing Start: Q1 2012 60 women |
|
CONRAD 118 PK Study of TFV Gel with Three Commonly Used Vaginal Products |
Interaction of TFV gel and antifungal cream, antimicrobial gel and contraceptive ring |
University of California, San Francisco Bronx-Lebanon Hospital |
Pending Start: target Q2 2013 45 women |
|
CONRAD 117 PK/PD and Safety Study of TFV/FTC Vaginal Tablet |
Assessing safety, PK/PD and acceptability of the combination TFV/FTC vaginal tablet |
EVMS TBD |
Ongoing Start: Q1, 2013 48 women |
|
PK/PD and Safety Study of TFV Intravaginal Ring (IVR) 120 |
Assessing safety and PK/PD of TFV IVR |
EVMS Albert Einstein College of Medicine |
Protocol in development Start: pending, target Q4 2012 |
|
PK/PD and Safety Study of TFV/Levonorgestrel (LNG) IVR 121 |
Assessing safety and PK/PD of TFV/LNG IVR |
EVMS TBD |
Protocol in development Start: pending, target Q4 2012 |
|
Postcoital Testing of TFV Gel/SILCS Diaphragm 122 |
Assessing ability of TFV gel/SILCS diaphragm to prevent sperm from penetrating cervical mucous |
EVMS |
Protocol in development Start: target 2013 |
|
PK/PD and Safety Study of TFV Gel/SILCS Diaphragm 123 |
Assessing safety and PK/PD of TFV gel/SILCS diaphragm |
TBD |
Protocol in development Start: target 2013 |